Rejuran vs Skin Botox: Which Is Better for Pores and Fine Lines?

Rejuran and Skin Botox are both popular injectable treatments in Korea for improving skin texture, pores, and fine lines, but they work in very different ways. Rejuran focuses on skin repair and regeneration, while Skin Botox uses micro-doses of botulinum toxin to refine pores, reduce oil production, and soften superficial lines. For foreign patients visiting Seoul, the better option depends on whether the priority is long-term skin quality or a more immediate improvement in surface texture and pore appearance.



1. What Is the Difference Between Rejuran and Skin Botox?

The main difference is the active ingredient and where it works.

Rejuran

• Contains polynucleotides (PN).
• Is injected into the dermal layer of the skin.
• Focuses on skin repair and regeneration.
• May improve elasticity, texture, fine lines, and overall skin resilience.
• Results generally develop gradually over several weeks.

Rejuran is often considered when the skin looks thin, stressed, rough, or less resilient. It is a skin-quality treatment rather than a facial contouring procedure.

Skin Botox

• Uses botulinum toxin in highly diluted micro-doses.
• Is injected superficially into the skin rather than primarily into facial muscles.
• Can reduce the appearance of enlarged pores and fine surface lines.
• May reduce sebum production and create a smoother skin texture.
• Results tend to appear faster than those of regenerative skin treatments.

Skin Botox is also called Micro Botox, Mesobotox, or Dermatoxin in Korean clinics. Unlike conventional Botox, which targets muscles, Skin Botox is designed to act closer to the skin surface.

The simplest distinction is:

Rejuran = repair and regeneration

Skin Botox = pore refinement, oil control, and surface smoothing

2. Which Is Better for Pores and Fine Lines?

Both can be used for pores and fine lines, but they approach these concerns differently.

Rejuran may be considered for:

• Enlarged-looking pores associated with poor skin quality
• Fine lines
• Rough texture
• Reduced elasticity
• Thin or fragile-looking skin
• Uneven skin texture
• Overall skin regeneration

Rejuran's effects are gradual because the treatment is designed to support the skin's repair processes. Some Korean clinical guides specifically describe Rejuran as useful for fine lines, pores, texture, and elasticity.

Skin Botox may be considered for:

• Enlarged pores
• Excessive facial oil
• Fine surface lines
• Rough-looking texture
• Facial shine
• Mild superficial wrinkles
• Desire for a smoother, more refined finish

Skin Botox can be particularly relevant when large pores and excess sebum occur together. By targeting the superficial skin layer and oil glands, it may create a tighter-looking and less oily appearance.

If your pores are mainly associated with oily skin and excess sebum, Skin Botox may be considered. If your pores are accompanied by thin, damaged, or aging skin, Rejuran may be more relevant.

3. Which One Is Better for Different Skin Types?

Skin type can make a significant difference when choosing between the two.

Oily or combination skin

Skin Botox may be considered when the main concerns are:

• Excess sebum
• Enlarged pores
• Facial shine
• Fine surface lines

Rejuran can still be used when skin quality and elasticity are also concerns.

Dry or dehydrated skin

Rejuran may be more relevant when dryness is accompanied by:

• Thin skin
• Fine lines
• Reduced elasticity
• Rough texture
• A compromised-looking skin barrier

Skin Botox is not primarily a hydration treatment, so another hydration-focused treatment may sometimes be considered alongside or instead of it.

Sensitive or stressed skin

Rejuran may be considered when the goal is to improve overall skin resilience. However, active skin conditions or significant irritation should be evaluated before receiving any injectable procedure.

Mature skin

Both treatments may have a role, but they address different concerns.

• Rejuran: skin quality, elasticity, fine lines
• Skin Botox: pores, sebum, superficial lines, texture

The best choice depends on what is causing the visible concern, not simply your skin type.

4. Treatment Process, Results and Downtime

The procedures are both minimally invasive but have different treatment experiences.

Rejuran treatment

A typical session includes:

1. Consultation and skin assessment
2. Cleansing and preparation
3. Topical or local numbing
4. Multiple small Rejuran injections
5. Cooling or soothing care

Temporary redness, swelling, tenderness, bruising, and small raised injection bumps can occur. Korean treatment guides commonly describe these visible injection marks as settling within several days.

Rejuran generally produces gradual results, with skin texture and elasticity improving progressively over several weeks. A series of sessions may be recommended depending on the condition of the skin.

Skin Botox treatment

A typical session includes:

1. Consultation and skin assessment
2. Cleansing and preparation
3. Numbing when necessary
4. Multiple micro-injections across the skin
5. Cooling or soothing care

Because the injections are superficial and use small amounts of toxin, downtime is usually limited. Temporary redness, small bumps, swelling, or bruising can occur.

Skin Botox effects may begin within several days and become more noticeable over the following one to two weeks. The effects are temporary and commonly last a few months, depending on the product, dose, technique, and individual response.

Patients should follow the clinic's aftercare instructions and avoid unnecessary irritation, excessive heat, alcohol, or strenuous exercise when advised.

5. How Much Do Rejuran and Skin Botox Cost in Korea?

Prices vary according to the product, toxin brand, dosage, treatment area, injection technique, clinic, and promotional pricing.

As a general 2026 Seoul price guide:

Rejuran

• 1cc: approximately ₩150,000–₩300,000
• 2cc: approximately ₩200,000–₩500,000
• 4cc: approximately ₩400,000–₩800,000+
• Larger treatment plans: approximately ₩800,000–₩1,000,000+

Skin Botox

• Small area: approximately ₩50,000–₩150,000
• Full face: approximately ₩100,000–₩300,000+
• Premium imported toxin brands: approximately ₩200,000–₩500,000+
• Face and neck or larger areas: approximately ₩300,000–₩600,000+

Prices can vary substantially because Skin Botox may use different botulinum toxin brands and doses. Some clinics also offer different prices for Korean and imported toxin products.

Foreign patients should confirm:

• Exact Rejuran formulation or toxin brand
• Amount or units used
• Treatment area
• Injection technique
• Whether numbing is included
• Whether VAT is included
• Whether the price is promotional

Do not compare the two treatments only by price. Rejuran and Skin Botox have different ingredients, treatment goals, and dosing systems.

6. Which Should Foreign Patients Choose in Korea?

The easiest way to decide is to identify what is driving your pore and fine-line concerns.

Consider Rejuran if your priorities are:

• Skin regeneration
• Fine lines
• Reduced elasticity
• Thin or stressed skin
• Rough texture
• Long-term improvement in skin quality

Consider Skin Botox if your priorities are:

• Enlarged pores
• Excess sebum
• Facial shine
• Fine surface lines
• Smoother texture
• A more refined appearance in a relatively short period

Some patients may benefit from both treatments because they address different layers of the problem. For example, Skin Botox may be used for pore and oil control while Rejuran is used as part of a longer-term skin-quality treatment plan. Combining treatments should be planned by a qualified medical professional based on the patient's skin condition.

For international patients visiting Seoul, ask the clinic to explain the exact product, dosage, injection depth, treatment area, expected timeline, downtime, and total price before treatment.

Frequently Asked Questions

Is Rejuran or Skin Botox better for enlarged pores?
Both may help, but Skin Botox is particularly relevant when enlarged pores are associated with excess sebum. Rejuran may be considered when poor skin quality, elasticity, or texture also contributes to the appearance of pores.

Which is better for fine lines?
Skin Botox may be useful for superficial expression-related or surface lines, while Rejuran may be considered for fine lines associated with declining skin quality and elasticity.

Does Skin Botox freeze your face?
Skin Botox uses much smaller, superficial doses than conventional muscle-targeting Botox. The goal is to improve skin texture and pores while preserving natural expression, although excessive dosing or inappropriate placement can still affect movement.

Is Rejuran more painful than Skin Botox?
Both involve multiple injections, so discomfort varies. Rejuran is commonly described as relatively uncomfortable even with numbing because many small injections are used. Skin Botox also involves multiple injections, but the experience depends on the area, technique, and numbing method.

How long do Skin Botox results last?
Results are temporary and commonly last around two to four months, although duration varies according to toxin type, dose, technique, and individual response.

Can foreigners get Rejuran and Skin Botox in Seoul?
Yes. Both treatments are widely offered at Korean dermatology and aesthetic clinics. International patients should confirm the exact product, dosage, treatment area, price, and aftercare instructions before booking.

Final Thoughts

Rejuran and Skin Botox can both improve the appearance of pores and fine lines, but Rejuran focuses more on skin repair and long-term quality, while Skin Botox targets pores, sebum, and superficial texture.

For foreign patients visiting Korea, consider whether your priority is regenerating the skin or refining its surface appearance. A personalized consultation can help determine whether one treatment or a combination approach is appropriate for your skin.